URIC ACID LEVELS IN MOTORCYCLE WORKSHOP WORKERS IN PEKANBARU CITY

Alfin Surya, Rekha Astuty, Mega Pratiwi Irawan, Rosa Devitria, Fatma Fatma, Hesti Marliza, Zaiyar Zaiyar

Sari


A byproduct of purine metabolism is uric acid, which can cause hyperuricemia and increase the risk of gout and other metabolic diseases when blood levels are too high. Long-term exposure to lubricants, vehicle exhaust, and carbon monoxide can increase uric acid levels in motorcycle repair workers. The heart and kidneys, which are important for uric acid metabolism and excretion, may be affected by exposure to substances found in motor vehicle lubricants and exhaust fumes. Additionally, the sedentary work habits of workshop workers, which involve little physical activity, can disrupt kidney function and delay the elimination of uric acid from the body. Therefore, due to the combination of lifestyle and work environment characteristics, motorcycle repair shop workers can be considered a high-risk category for developing gout. However, there is still a lack of information about uric acid levels in this population, particularly in Pekanbaru City. The purpose of this investigation is to determine the uric acid levels of employees at motorcycle workshop X in Pekanbaru City. Samples were taken from employees who met the inclusion and exclusion criteria using a descriptive cross-sectional methodology. The Point-of-Care Testing (POCT) approach, along with strip testing, is used to assess uric acid. According to findings from 24 respondents, 3 workers (12.5%) experienced increased uric acid levels, while 21 workers (87.5%) had normal levels. At 5.44 mg/dL, the average uric acid level is within the reference range. These findings indicate that prolonged working hours and occupational exposure elevate the risk of hyperuricemia, despite the majority of employees exhibiting normal uric acid levels. To reduce the burden of metabolic diseases on the high-risk working population, this study emphasizes the importance of occupational health surveillance and preventive measures.

Keywords: Uric acid, Motorcycle workshop workers, Hyperuricemia, Occupational exposure.

 


Teks Lengkap:

PDF

Referensi


Ainurrozaq, I., Arifin, M. Z., & Rahmawati, A. (2020). GAMBARAN MORFOLOGI ERITROSIT PADA PEKERJA BENGKEL MOTOR YANG SERING TERPAPAR LB3(Limbah Bahan Bakar Beracun). In Jurnal Insan Cendekia (Vol. 7, Issue 2).

Al-Batool, W., Al-Batool, H., Hassan, A., Zarecka, I., Hassan, S., Bienia, S., Kossakowska, A., Leicht, J., & Konieczna, K. (2025). Carbon monoxide poisoning: Pathophysiology, diagnosis, symptoms and advances in acute and chronic management. Medical Science, 29(155), 1–10. https://doi.org/10.54905/disssi.v29i155.e9ms3482

Burnier, M. (2023). Gout and hyperuricaemia: modifiable cardiovascular risk factors? In Frontiers in Cardiovascular Medicine (Vol. 10). Frontiers Media S.A. https://doi.org/10.3389/fcvm.2023.1190069

Chen, X. Y., Lu, F., Zhang, J., Xu, C. X., Du, X. F., Liang, M. Bin, Chen, L. J., & Zhong, J. M. (2024). The effect of hyperuricemia and its interaction with hypertension towards chronic kidney disease in patients with type 2 diabetes: evidence from a cross- sectional study in Eastern China. Frontiers in Endocrinology, 15. https://doi.org/10.3389/fendo.2024.1415459

Chen, Y., Yang, Y., Zheng, Z., Wang, H., Wang, X., Si, Z., Meng, R., Wang, G., & Wu, J. (2022a). Influence of occupational exposure on hyperuricemia in steelworkers: a nested case–control study. BMC Public Health, 22(1). https://doi.org/10.1186/s12889-022-13935-x

Chen, Y., Yang, Y., Zheng, Z., Wang, H., Wang, X., Si, Z., Meng, R., Wang, G., & Wu, J. (2022b). Influence of occupational exposure on hyperuricemia in steelworkers: a nested case–control study. BMC Public Health, 22(1). https://doi.org/10.1186/s12889-022-13935-x

Cicero, A. F. G., Fogacci, F., Di Micoli, V., Angeloni, C., Giovannini, M., & Borghi, C. (2023). Purine Metabolism Dysfunctions: Experimental Methods of Detection and Diagnostic Potential. In International Journal of Molecular Sciences (Vol. 24, Issue 8). Multidisciplinary Digital Publishing Institute (MDPI). https://doi.org/10.3390/ijms24087027

Dong, H., Cao, Y., Ding, X., Yan, T., Zhou, C., Bi, M., Wang, H., Wang, X., & Li, J. (2024). The influence of night shift work and associated factors on serum uric acid in aircraft maintenance workers. BMC Public Health, 24(1). https://doi.org/10.1186/s12889-024-18849-4

Kar, S., Chowdhury, S., Gupta, T., Hati, D., De, A., Ghatak, Z., Tinab, T., Rahman, I. T., Chatterjee, S., & RoyChowdhury, A. (2024). A Study on the Impact of Air Pollution on Health Status of Traffic Police Personnel in Kolkata, India. Air, 2(1), 1–23. https://doi.org/10.3390/air2010001

Lu, J., Sun, W., Cui, L., Li, X., He, Y., Liu, Z., Li, H., Han, L., Ji, A., Wang, C., Zhang, H., Ji, X., Ren, W., Wang, X., & Li, C. (2020). A cross-sectional study on uric acid levels among Chinese adolescents. Pediatric Nephrology, 35(3), 441–446. https://doi.org/10.1007/s00467-019-04357-w

Mei, Y., Dong, B., Geng, Z., & Xu, L. (2022). Excess Uric Acid Induces Gouty Nephropathy Through Crystal Formation: A Review of Recent Insights. In Frontiers in Endocrinology (Vol. 13). Frontiers Media S.A. https://doi.org/10.3389/fendo.2022.911968

Nancy, U. L., Pegram, M., Sahebjam, S., Ibrahim, N., Fung, A., Cheng, A., Nicholas, A., Kirschbrown, W., & Kumthekar, P. (2021). Reply to J. Wei et al. In Journal of Clinical Oncology (Vol. 39, Issue 36, pp. 4127–4128). Lippincott Williams and Wilkins. https://doi.org/10.1200/JCO.21.01973

Prasetya, T. A. E., Samad, N. I. A., Rahmania, A., Arifah, D. A., Rahma, R. A. A., & Al Mamun, A. (2024). Workstation Risk Factors for Work-related Musculoskeletal Disorders Among IT Professionals in Indonesia. Journal of Preventive Medicine and Public Health, 57(5), 451–460. https://doi.org/10.3961/jpmph.24.214

Tang, Y. X., Zhang, Y. T., Xu, Y. J., Qian, Z. (Min), Vaughn, M. G., McMillin, S. E., Chen, G. B., Song, H. D., Lu, Y. J., Li, Y. R., Dong, G. H., & Wang, Z. (2023). Exposure to ambient particulate matter and hyperuricemia: An eight-year prospective cohort study on male traffic officers in China. Ecotoxicology and Environmental Safety, 249. https://doi.org/10.1016/j.ecoenv.2022.114354

Wei, K. Y., Liao, C. Y., Chung, C. H., Lin, F. H., Tsao, C. H., Sun, C. A., Lu, K. C., Chien, W. C., & Wu, C. C. (2021). Carbon Monoxide Poisoning and Chronic Kidney Disease Risk: A Nationwide, Population-Based Study. American Journal of Nephrology, 52(4), 292–303. https://doi.org/10.1159/000515383

Zhang, Z., Chen, Y., Chen, Y., Xiong, M., Pang, Z., Liu, G., Zhao, H., Jiang, L., & Chen, Q. (2025). Impact of shift work and obesity on risk of hyperuricemia in coal miners: A cross-sectional design based dose-response relationships and interaction analysis. Journal of Environmental and Occupational Medicine, 42(4), 451–458. https://doi.org/10.11836/JEOM24370




DOI: https://doi.org/10.33559/eoj.v8i1.3546

Refbacks

  • Saat ini tidak ada refbacks.


Jumlah Kunjungan

Negara Pengunjung

Flag Counter

Lisensi Creative Commons
Ciptaan disebarluaskan di bawah Lisensi Creative Commons Atribusi 4.0 Internasional.